Technology
The FluoRa system
A patented optical guidance platform for neurosurgery that integrates fluorescence, microcirculation and tissue identification into a single device and software. Optical probes are available for stereotactic guidance with the Leksell Stereotactic System and StealthStation, one-insertion needle biopsy, and hand-held measurements during resection.
Fluorescence
Probe-based 5-ALA fluorescence spectroscopy quantifies protoporphyrin IX in situ, enabling objective high-grade tumour detection at a lower ALA dose — with or without the blue-light microscope.
Microcirculation
High-resolution laser Doppler flowmetry provides a real-time vessel alarm along the insertion trajectory, supporting safe advancement toward a pre-calculated target.
Tissue identification
Continuous grey–white matter discrimination indicates shades of tissue along the insertion line, adding an anatomical reference to navigation and stereotactic frames.
From research to regulatory approval
Prototype 1
Separate systems
Fluorescence and laser Doppler flowmetry operated as two independent systems with separate software.
FluoRa 1.0
Unified software
Both modalities retained as separate hardware but controlled through one clinical software interface.
FluoRa 2.0
Technology transfer
Fluorescence and flowmetry integrated into a single device; clinical investigation carried out in neurosurgery.
FluoRa 3.0
CE and FDA pathway
Complete optical guidance system in preparation for CE marking, with the FDA pathway identified.
Intellectual property
Granted patents
Core method and device claims covering combined fluorescence and microcirculation measurement are granted in key markets.
Know-how and data
Proprietary algorithms, calibration methods and a clinical dataset built over fifteen years of measurements.
Freedom to operate
Probe designs compatible with established stereotactic and navigation platforms from Elekta and Medtronic.